Thymogen
Thymogen (Glutamyl-Tryptophan)
The simplest thymic peptide: just two amino acids
Thymogen is a synthetic dipeptide (Glu-Trp) developed in Russia as an immune modulator. Despite being only two amino acids, it has demonstrated T-cell modulatory activity in Russian clinical studies.
Admin routes
Intranasal, Intramuscular
Popularity
Niche
Side effects
Generally mild
AU vendors
0 rated
✓Key benefits
📈What to expect
Possible improvement in immune markers
Normalisation of T-cell subsets reported in Russian literature
Based on community reports and published research. Individual results vary significantly.
💊Dosing protocols
Immune support (Russian protocol)
100 mcg
Intranasal, once daily
5-10 day courses, repeated as needed
Immune restoration (injectable)
100 mcg
Intramuscular, once daily
3-10 day course
Dosing information is sourced from published research and community protocols. This is not a recommendation. Consult a healthcare professional.
Research status|Registered pharmaceutical in Russia; limited Western data
Overview
Thymogen was developed at the Institute of Bioregulation and Gerontology in Saint Petersburg as part of the Khavinson peptide bioregulator program. It is one of the simplest bioactive peptides known: just two amino acids (glutamic acid and tryptophan). In Russian medicine, it is registered as a pharmaceutical for immune deficiency states, chronic infections, and post-surgical immune recovery. It is available as both injectable and intranasal formulations. Western peer-reviewed data is limited, but Russian clinical studies report effects on T-cell differentiation and immune function restoration.
⚙️How it works
The exact mechanism is not fully characterised in Western literature. Russian researchers propose that the Glu-Trp sequence interacts with thymic epithelial cells to promote T-cell maturation and differentiation. It is reported to normalise the CD4/CD8 ratio, enhance thymic output of naive T-cells, and modulate cytokine profiles toward balanced Th1/Th2 responses.
⚡Side effects
📅Research history
Thymogen developed at the Saint Petersburg Institute of Bioregulation
Khavinson publishes on thymic peptides and longevity
References
- [1]Khavinson VK, Morozov VG. 'Peptides of pineal gland and thymus prolong human life.' Neuroendocrinology Letters, 2003.
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Disclaimer: This guide is for educational and informational purposes only. It is not medical advice. The dosing protocols listed are sourced from published research and community reports and do not constitute a recommendation. Always consult a qualified healthcare professional before using any peptide. Australian regulations classify many peptides as Schedule 4 (prescription-only) substances. Check current TGA guidelines before purchasing.