Peptide Guides

The recovery peptide backed by 30+ years of research

BPC-157 is a synthetic peptide derived from a naturally occurring protein in human gastric juice. Research suggests it accelerates healing of tendons, ligaments, muscles, and the gut lining.

Systemic tissue repair - from tendons to cardiac muscle

TB-500 is a synthetic fragment of Thymosin Beta-4, a naturally occurring peptide involved in tissue repair, cell migration, and inflammation regulation.

The anti-inflammatory tripeptide derived from α-MSH

KPV is a tripeptide fragment of alpha-melanocyte-stimulating hormone with potent anti-inflammatory properties, particularly for gut inflammation.

The copper peptide your skin used to make on its own

GHK-Cu is a naturally occurring copper peptide that declines with age. Research links it to collagen synthesis, wound healing, anti-inflammatory effects, and gene expression modulation.

The copper-free tripeptide for tissue remodelling

GHK is the base tripeptide (without copper) that signals tissue remodelling. While GHK-Cu gets more attention, GHK alone has significant biological activity.

The GLP-1 agonist behind the weight loss revolution

Semaglutide is a GLP-1 receptor agonist originally developed for type 2 diabetes. It has become one of the most discussed compounds in weight management, with clinical trials showing 15–17% body weight reduction.

The dual-action GLP-1 that outperforms Ozempic in every trial

Tirzepatide is a dual GIP/GLP-1 receptor agonist that has shown up to 20.9% body weight reduction in clinical trials - surpassing semaglutide in head-to-head comparisons.

The HGH fragment that targets fat without the side effects

AOD-9604 is a modified fragment of human growth hormone (amino acids 176-191) that stimulates fat metabolism without affecting blood sugar or growth. Originally developed as an anti-obesity drug.

The triple agonist showing 24% weight loss in trials

Retatrutide is a next-generation triple hormone receptor agonist (GIP, GLP-1, and glucagon) in Phase 3 clinical trials. Early data showed up to 24.2% body weight reduction - the most ever seen in a drug trial.

The NNMT inhibitor that targets stubborn fat at the cellular level

5-Amino-1MQ is a small molecule that inhibits NNMT, an enzyme linked to fat cell expansion and metabolic dysfunction. It represents a novel approach to fat loss that works at the epigenetic level.

The natural hormone behind the weight loss revolution

GLP-1 is the incretin hormone that semaglutide and tirzepatide mimic. Understanding native GLP-1 is key to understanding the entire GLP-1 agonist class.

The only known compound that activates telomerase in humans

Epithalon is a synthetic tetrapeptide based on Epithalamin, a natural extract from the pineal gland. Research suggests it activates telomerase, the enzyme that maintains telomere length - a key marker of biological aging.

The cellular fuel molecule that declines 50% by middle age

NAD+ is a coenzyme found in every living cell, essential for energy metabolism, DNA repair, and sirtuin activation. Levels decline significantly with age, driving interest in supplementation via IV, injection, and precursors.

The exercise-mimicking peptide encoded in your mitochondrial DNA

MOTS-c is a mitochondrial-derived peptide that activates AMPK, the same pathway triggered by exercise. Research links it to improved metabolic function, insulin sensitivity, and exercise performance.

The master antioxidant your cells depend on

Glutathione is the body's most abundant antioxidant, found in every cell. It neutralises free radicals, supports detoxification, and declines significantly with age.

The growth hormone secretagogue stack that works while you sleep

CJC-1295 and Ipamorelin are two peptides commonly stacked to stimulate natural growth hormone release. Together, they amplify the body's own GH pulsatile pattern without suppressing natural production.

Three times more potent than native IGF-1

IGF-1 LR3 is a modified version of insulin-like growth factor 1 with enhanced potency and longer half-life. Used in muscle-building and anti-aging research.

The original GH-releasing peptide - FDA-approved since 1997

Sermorelin is a synthetic analog of GHRH that stimulates natural growth hormone production from the pituitary. One of the few peptides with FDA approval history.

The cleanest growth hormone secretagogue available

Ipamorelin is a selective GH secretagogue that stimulates growth hormone release without affecting cortisol, prolactin, or appetite. Often considered the safest GH peptide.

The strongest GH secretagogue - with cardioprotective effects

Hexarelin produces the largest GH release of any secretagogue and has unique cardioprotective properties. More potent than ipamorelin but with a less selective profile.

FDA-approved GHRH analog that reduces visceral fat

Tesamorelin is an FDA-approved GHRH analog specifically indicated for reducing visceral adipose tissue. One of the few peptides with current regulatory approval.

The original GH secretagogue - potent but hungry

GHRP-6 was one of the first synthetic GH secretagogues. It produces significant GH release but is known for dramatically increasing appetite.

The oral GH secretagogue - no injection required

MK-677 (ibutamoren) is an orally active, non-peptide GH secretagogue. It raises GH and IGF-1 levels for up to 24 hours from a single oral dose.

The Russian nootropic peptide with 30 years of clinical use

Semax is a synthetic peptide analogue of ACTH(4-10) developed in Russia. It has been approved there since the 1990s for cognitive enhancement, stroke recovery, and neuroprotection.

The anxiolytic peptide that enhances cognition without sedation

Selank is a synthetic peptide analogue of the immunomodulatory protein tuftsin, developed in Russia alongside Semax. It has been approved in Russia since 2009 for anxiety and cognitive enhancement.

Seven orders of magnitude more potent than BDNF

Dihexa is a small peptide analog of angiotensin IV that crosses the blood-brain barrier and dramatically enhances cognitive function in animal models.

Fast-acting antidepressant peptide via TREK-1 channels

PE-22-28 is a synthetic analog of spadin that blocks TREK-1 potassium channels. Research shows antidepressant effects within 4 days versus weeks for SSRIs.

Russian neuropeptide complex used clinically for decades

Cortexin is a mixture of neuropeptides derived from animal cerebral cortex. Clinically approved in Russia for stroke recovery, cognitive disorders, and neuroprotection.

Neurotrophic peptide mixture with 50+ years of clinical use

Cerebrolysin is a porcine brain-derived peptide preparation used clinically worldwide for stroke, dementia, and traumatic brain injury. Approved in 40+ countries.

The peptide that promotes deep restorative sleep

DSIP is a neuropeptide that promotes delta wave (deep) sleep, modulates stress hormones, and has been studied for its pain-modulating and hormonal-balancing effects.

The immune-modulating peptide approved in 30+ countries

Thymosin Alpha-1 is a thymic peptide that modulates immune function by enhancing T-cell maturation and function. It is approved as a pharmaceutical (Zadaxin) in over 30 countries for hepatitis and immune deficiency.

Your body's frontline antimicrobial peptide

LL-37 is the only cathelicidin antimicrobial peptide in humans. It kills bacteria, viruses, and fungi on contact and modulates the immune response.

The neuroimmune peptide for mould illness and CIRS

VIP is a 28-amino-acid neuropeptide with potent anti-inflammatory and immune-regulating properties. Central to CIRS (chronic inflammatory response syndrome) treatment protocols.

The thymus peptide that declines with immune aging

Thymulin is a nonapeptide hormone produced by the thymus gland, essential for T-cell maturation and immune regulation. Levels decline dramatically with thymic involution.

The tanning peptide with unexpected effects on libido and appetite

Melanotan 2 is a synthetic analogue of alpha-MSH that stimulates melanogenesis (tanning), increases libido, and reduces appetite. It is one of the most widely used peptides in Australia despite lacking regulatory approval.

The only FDA-approved peptide specifically for sexual dysfunction

PT-141 (Bremelanotide) is a melanocortin receptor agonist that works in the brain to increase sexual desire. It is FDA-approved as Vyleesi for hypoactive sexual desire disorder in women.

The master regulator of reproductive hormones

Kisspeptin is a neuropeptide that controls the release of GnRH, the master hormone that drives testosterone, oestrogen, LH, and FSH production. It is being studied for fertility, hypogonadism, and hormonal recovery.

The hormone that preserves fertility on TRT

HCG mimics luteinizing hormone, stimulating testosterone production and maintaining testicular function. Critical for men on TRT who want to preserve fertility.

The bonding hormone with far-reaching effects

Oxytocin is a nine-amino-acid peptide hormone known for its role in social bonding, trust, and reproduction. Increasingly researched for anxiety, autism, and metabolic effects.