Cortexin
Cortexin (Neuropeptide Complex)
Russian neuropeptide complex used clinically for decades
Cortexin is a mixture of neuropeptides derived from animal cerebral cortex. Clinically approved in Russia for stroke recovery, cognitive disorders, and neuroprotection.
Admin routes
Intramuscular, Intranasal
Popularity
Niche
Side effects
Monitor closely
Vendors
0 rated
Key benefits
What to expect
Improved cognitive clarity; reduced brain fog
Enhanced memory and concentration
Full neuroprotective course completed
Repeat course for sustained benefits
Based on community reports and published research. Individual results vary significantly.
Dosing protocols
Cognitive support (IM)
10 mg
Once daily
10-day courses, repeated 2–4 times per year
Intranasal
1 mg per spray, 3 sprays daily
Three times daily
2-week cycles
Dosing information is sourced from published research and community protocols. This is not a recommendation. Consult a healthcare professional.
Research status|Approved in Russia - limited Western clinical data
Overview
Cortexin is a complex mixture of low-molecular-weight neuropeptides, amino acids, and minerals extracted from the cerebral cortex of young cattle or pigs. It has been clinically approved in Russia and several CIS countries since the 1990s for treating cognitive disorders, stroke recovery, traumatic brain injury, and epilepsy. It is one of the most prescribed neuroprotective agents in Russian clinical medicine.
How it works
Targets multiple neurological pathways simultaneously: binds glutamatergic and GABAergic receptors (AMPA, kainate, mGluR1/5, GABA-A), inhibits caspase-8 (preventing apoptosis during excitotoxicity), enhances GABA and serotonin neurotransmission, provides antioxidant effects, and stimulates axonal and dendritic growth through neurotrophic factor expression.
Side effects
Research history
Developed by Geropharm in St. Petersburg, Russia
Approved for clinical use in Russia
Widely prescribed for stroke, TBI, and cognitive disorders in CIS countries
Published clinical data exceeds 10,000 patients
Growing availability through international peptide suppliers
Russian clinical experience
Cortexin has been used clinically in Russia since the 1990s with over 10,000 patients in published studies. Russian clinical data supports its use for ischaemic stroke recovery, cognitive impairment, and paediatric neurological conditions. That said, these studies generally do not meet Western randomised controlled trial standards, and cortexin has not been evaluated by the FDA or TGA.
Recommended products
Hand-picked for this compound. Ships via Amazon 🇺🇸
Core Supplies
Bacteriostatic Water 30mL
Storage & Transport
Portable Insulin Cooler Fridge
Further Reading
Peptide Protocols
References
- [1]Shabanov PD, et al. 'Neuroprotective properties of cortexin: experimental and clinical studies.' Medical Academic Journal, 2016.
- [2]Gusev EI, Skvortsova VI. 'Brain ischemia.' Kluwer Academic Publishers, 2003.
Frequently asked questions
Related peptides
Community experiences
Share your experience with Cortexin. Effects, side effects, protocol details - help others make informed decisions.
No community reviews yet. Be the first to share your experience with Cortexin.
Need to calculate your dose?
Use our free reconstitution calculator to work out syringe units for Cortexin.
Open CalculatorFound this useful?
Share this guide
Get the free Beginner Peptide Protocol
Which peptides to start with, what to avoid, and safe handling. Delivered to your inbox.
Vendors
Rated suppliers
Quality, shipping, and service scores
Store
Supplies
Syringes, bac water, storage
Guides
How-to guides
Storage, reconstitution, and travel
Disclaimer: This guide is for educational and informational purposes only. It is not medical advice. The dosing protocols listed are sourced from published research and community reports and do not constitute a recommendation. Always consult a qualified healthcare professional before using any peptide. Check your local regulations regarding peptide purchase and use.